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16,761 samples completed from 41 states. Last updated Friday, October 17, 2025.
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603565

From Roanoke, Virginia on September 25, 2025

Assumed to be heroin

This is a messy brew of 8 major substances:

  • acetaminophen
  • caffeine
  • lidocaine
  • xylazine
  • procaine
  • 4-ANPP
  • fentanyl
  • bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate

But we found lots of contaminants too, with traces of dimethyl sulfone (methylsulfonylmethane MSM) + medetomidine + tramadol + cocaine. Trace substances in small quantities are usually harmless, but can sometimes cause health problems. Unexpected sensations may be due to these.

Fentanyl is potent and the amount changes by batch. If you weren't expecting it, consider getting test strips online or from a harm reduction program. Carry naloxone (Narcan) to reverse overdoses. Don't use alone so someone can help if you go out.

Xylazine causes serious skin problems. These can happen anywhere on the body and don't heal quickly. And, xylazine can come on stronger than traditional dope and knock you out, so be mindful of your surroundings. It's best to avoid dope with xylazine. You might need medical attention to prevent long-term damage.

There are a lot of different substances in this sample. We don't know the harms that some of these can cause. Be careful and be prepared for unexpected reactions.

Looks = light brown, tan, fine, dull, powder

Need free supplies and advice to keep you safe? Find your nearest harm reduction program at harmreduction.org

Major substances in graph:

Peak: 6.24 = acetaminophen

Peak: 6.88 = caffeine

Peak: 7 = lidocaine

Peak: 7.41 = xylazine

Peak: 7.56 = procaine

Peak: 9.02 = 4-ANPP

Peak: 10.12 = fentanyl

Peak: 12.01 = bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate

Method(s): GCMS

Record for Sample 603565 last updated October 17, 2025