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18,182 samples completed from 41 states. Last updated Friday, December 19, 2025.
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604545

From Asheboro, North Carolina on November 1, 2025

Assumed to be fentanyl, xylazine, medetomidine

This is a messy brew of 9 major substances:

  • dimethyl sulfone (methylsulfonylmethane MSM)
  • 1,3-Diacetin
  • medetomidine
  • xylazine
  • procaine
  • 4-ANPP
  • despropionyl ortho-methylfentanyl
  • fentanyl
  • ortho-methylfentanyl

And we also found traces of heroin + phenethyl 4-ANPP. Trace substances in small quantities are usually harmless, but can sometimes cause health problems. Unexpected sensations may be due to these.

Fentanyl is potent and the amount changes by batch. If you weren't expecting it, consider getting test strips online or from a harm reduction program. Carry naloxone (Narcan) to reverse overdoses. Don't use alone so someone can help if you go out.

Xylazine causes serious skin problems. These can happen anywhere on the body and don't heal quickly. And, xylazine can come on stronger than traditional dope and knock you out, so be mindful of your surroundings. It's best to avoid dope with xylazine. You might need medical attention to prevent long-term damage.

There are a lot of different substances in this sample. We don't know the harms that some of these can cause. Be careful and be prepared for unexpected reactions.

Looks = gray, unknown texture

Need free supplies and advice to keep you safe? Find your nearest harm reduction program at harmreduction.org

Major substances in graph:

Peak: 2.25 = dimethyl sulfone (methylsulfonylmethane MSM)

Peak: 4.55 = 1,3-Diacetin

Peak: 7.23 = medetomidine

Peak: 7.4 = xylazine

Peak: 7.55 = procaine

Peak: 9 = 4-ANPP

Peak: 9.24 = despropionyl ortho-methylfentanyl

Peak: 10.09 = fentanyl

Peak: 10.4 = ortho-methylfentanyl

Method(s): GCMS

Record for Sample 604545 last updated December 9, 2025